A common objection to Christianity is that people don’t like the concept that they could be condemned, despite being “good” people. Ignoring the difficulties around goodness and morality outside of God, people are opposed to the idea that they might deserve an adverse fate.
People like Oprah (to use the cheesy American pop-culture example) say they can’t deal with the idea of a God who condemns. They dismiss the concept of God, even hate the idea of God, because they dislike that their failure to acknowledge God could have eternally negative consequences.
It strikes me that this is quite similar to the attitude of Cain in Genesis 4.
The Lord said to Cain, “Why are you angry, and why has your face fallen? If you do well, will you not be accepted? And if you do not do well, sin is crouching at the door. Its desire is for you, but you must rule over it.” (Genesis 4:6, 7 ESV)
Cain is understandably disappointed to have his sacrifice effectively rejected by God. But the reality is, his devotion to God was not real enough, and he was not ruling over his sinfulness – he skimped on his dedication to God. And he responds to the rebuke not with humility but anger – he rejects God’s rule and murder his brother.
To me, the parallel is pretty strong. People don’t want to commit their lives to Christ. But when they hear that a life that is not right with God (obviously there is a significant point of difference here, as we are under the new covenant rathe than the old) is not good enough, they don’t like it.
Sin still rules, they are not dedicated to their rightful Lord.
The majority of people, like Cain, fail to respond appropriately to God. People let sin rule. And instead of hearing God’s rebuke (through his Spirit and Word) humbly, they react with denial and  sometimes anger (be that actual emotional anger or mere intellectual lack of acceptance. They follow Cain’s example not necessarily with murder, but certainly in turning away from God’ command. This is not to say that that every person who rejects God does so out of anger. But for many people, hearing they are not right with God leads to rejection of God rather than repentance.
Ultimately, Cain suffers for his sin. Our society needs to understand that the world has already seen someone personify their attitude.